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1

Comparison of knee gait kinematics of workers exposed to knee straining posture to those of non-knee straining workers

Gaudreault, Nathaly, Hagemeister, Nicola, Poitras, Stéphane, de Guise, Jacques A.

Journal:

Year:

2013

Language:

english

File:

PDF, 546 KB

english, 2013

2

Truncated Area Under the Curve as a Measure of Relative Extent of Bioavailability: Evaluation Using Experimental Data and Monte Carlo Simulations

Jacques Gaudreault, Diane Potvin, Jean Lavigne, Richard L. Lalonde

Journal:

Pharmaceutical Research

Year:

1998

File:

PDF, 780 KB

1998

3

Kinematic gait analysis of workers exposed to knee straining postures by Bayes decision rule

Mezghani, Neila, Gaudreault, Nathaly, Mitiche, Amar, Ayoubian, Leila, Ouakrim, Youssef, Hagemeister, Nicola, Deguise, Jacques A

Journal:

Artificial Intelligence Research

Year:

2015

File:

PDF, 1.05 MB

2015

4

Cycloalkyl-substituted aryl chloroethylureas inhibiting cell cycle progression in G0/G1 phase and thioredoxin-1 nuclear translocation

Jessica S. Fortin, Marie-France Côté, Jacques Lacroix, Alexandre Patenaude, Éric Petitclerc, René C.-Gaudreault

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 606 KB

english, 2008

5

Effects of physiotherapy treatment on knee osteoarthritis gait data using principal component analysis

Nathaly Gaudreault, Neila Mezghani, Katia Turcot, Nicola Hagemeister, Karine Boivin, Jacques A. de Guise

Journal:

Clinical Biomechanics

Year:

2011

Language:

english

File:

PDF, 514 KB

english, 2011

6

PHARMACOKINETICS AND RETINAL DISTRIBUTION OF RANIBIZUMAB, A HUMANIZED ANTIBODY FRAGMENT DIRECTED AGAINST VEGF-A, FOLLOWING INTRAVITREAL ADMINISTRATION IN RABBITS

GAUDREAULT, JACQUES, FEI, DAVID, BEYER, JOSEPH C., RYAN, ANNE, RANGELL, LINDA, SHIU, VANESSA, DAMICO, LISA A.

Journal:

Year:

2007

Language:

english

File:

PDF, 810 KB

english, 2007

7

Pharmacokinetics and Anticonvulsant Effect of a New Hypnotic, CL 284,846, in Rats

Jacques Gaudreault, France Varin, Gary M. Pollack

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.09 MB

1995

8

Do prostacyclin and thromboxane contribute to the “protective effect” of pregnancies with chronic hypertension? A preliminary prospective longitudinal study

Jean-Marie Moutquin, Carmen Lindsay, Nicole Arial, Pierre De Grandpré, René C-Gaudreault, Jean-Claude Forest, Jacques Massé

Journal:

American Journal of Obstetrics and Gynecology

Year:

1997

Language:

english

File:

PDF, 790 KB

english, 1997

9

Admission to a pediatric intensive care unit for poisoning

LACROIX, JACQUES, GAUDREAULT, PIERRE, GAUTHIER, MARIE

Journal:

Critical Care Medicine

Year:

1989

File:

PDF, 251 KB

1989

10

IDENTIFICATION OF KNEE FRONTAL PLANE KINEMATIC PATTERNS IN NORMAL GAIT BY PRINCIPAL COMPONENT ANALYSIS

MEZGHANI, NEILA, FUENTES, ALEXANDRE, GAUDREAULT, NATHALY, MITICHE, AMAR, AISSAOUI, RACHID, HAGMEISTER, NICOLA, DE GUISE, JACQUES A.

Journal:

Journal of Mechanics in Medicine and Biology

Year:

2013

Language:

english

File:

PDF, 425 KB

english, 2013

11

N-Phenyl-N′-(2-chloroethyl)ureas (CEU) as potential antineoplastic agents. Part 2: Role of ω-hydroxyl group in the covalent binding to β-tubulin

Sébastien Fortin, Emmanuel Moreau, Alexandre Patenaude, Michel Desjardins, Jacques Lacroix, Jean L.C. Rousseau, René C-Gaudreault

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 275 KB

english, 2007

12

Clinical pharmacokinetics of bevacizumab in patients with solid tumors

Jian-Feng Lu, Rene Bruno, Steve Eppler, William Novotny, Bert Lum, Jacques Gaudreault

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 389 KB

english, 2008

13

Pharmacological control of platelet-leukocyte interactions by the human anti-P-selectin antibody inclacumab – preclinical and clinical studies

Kling, Dorothee, Stucki, Corinne, Kronenberg, Sven, Tuerck, Dietrich, Rhéaume, Eric, Tardif, Jean-Claude, Gaudreault, Jacques, Schmitt, Christophe

Journal:

Thrombosis Research

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

14

Abnormal occipital event-related potentials in Parkinson's disease with concomitant REM sleep behavior disorder

Gaudreault, Pierre-Olivier, Gagnon, Jean-François, Montplaisir, Jacques, Vendette, Mélanie, Postuma, Ronald B., Gagnon, Katia, Gosselin, Nadia

Journal:

Parkinsonism & Related Disorders

Year:

2013

Language:

english

File:

PDF, 346 KB

english, 2013

15

P34H Sperm Protein Is Preferentially Expressed by the Human Corpus Epididymidis 1

Légaré, Christine, Gaudreault, Christian, St-Jacques, Sylvie, Sullivan, Robert

Journal:

Year:

1999

Language:

english

File:

PDF, 1.03 MB

english, 1999

16

Chloroethyl urea derivatives block tumour growth and thioredoxin-1 nuclear translocation

Patenaude, Alexandre, Fortin, Jessica S., Deschenes, Réna, Côté, Marie-France, Lacroix, Jacques, C.-Gaudreault, René, Petitclerc, Éric

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

17

M-H-077 OCCIPITAL DYSFUNCTION IN PATIENTS WITH PARKINSON'S DISEASE AND REM SLEEP BEHAVIOUR DISORDER: AN EVENT-RELATED POTENTIAL STUDY

Pierre-Olivier Gaudreault, Jean-François Gagnon, Jacques Y. Montplaisir, Ronald Postuma, Nadia Gosselin

Journal:

Year:

2011

Language:

english

File:

PDF, 86 KB

english, 2011

18

Synthesis, antiproliferative activity evaluation and structure–activity relationships of novel aromatic urea and amide analogues of N-phenyl-N′-(2-chloroethyl)ureas

Sébastien Fortin, Emmanuel Moreau, Jacques Lacroix, Marie-France Côté, Éric Petitclerc, René C.-Gaudreault

Journal:

European Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 525 KB

english, 2010

19

Preclinical Pharmacokinetics of Ranibizumab (rhuFabV2) after a Single Intravitreal Administration

Gaudreault, Jacques, Fei, David, Rusit, Jeriza, Suboc, Pamela, Shiu, Vanessa

Journal:

Investigative Ophthalmology & Visual Science

Year:

2005

Language:

english

File:

PDF, 359 KB

english, 2005

20

N-Phenyl-N′-(2-chloroethyl)urea analogues of combretastatin A-4: Is the N-phenyl-N′-(2-chloroethyl)urea pharmacophore mimicking the trimethoxy phenyl moiety?

Sébastien Fortin, Emmanuel Moreau, Jacques Lacroix, Jean-Claude Teulade, Alexandre Patenaude, René C-Gaudreault

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 250 KB

english, 2007

21

Novel imidazo[1,2-a]naphthyridinic systems (part 1): Synthesis, antiproliferative and DNA-intercalating activities

Mounir Andaloussi, Emmanuel Moreau, Nicolas Masurier, Jacques Lacroix, René C. Gaudreault, Jean-Michel Chezal, Anas El Laghdach, Damien Canitrot, Eric Debiton, Jean-Claude Teulade, Olivier Chavignon

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 792 KB

english, 2008

22

Concomitant Administration of Bevacizumab, Irinotecan, 5-Fluorouracil, and Leucovorin: Nonclinical Safety and Pharmacokinetics

Gaudreault, Jacques, Shiu, Vanessa, Bricarello, Ann, Christian, Brian, Zuch, Christina, Mounho, Barbara

Journal:

International Journal of Toxicology

Year:

2005

Language:

english

File:

PDF, 100 KB

english, 2005

23

First-in-man Study With Inclacumab, a Human Monoclonal Antibody Against P-selectin

Schmitt, Christophe, Abt, Markus, Ciorciaro, Cornelia, Kling, Dorothee, Jamois, Candice, Schick, Eginhard, Solier, Corinne, Benghozi, Renée, Gaudreault, Jacques

Journal:

Journal of Cardiovascular Pharmacology

Year:

2015

Language:

english

File:

PDF, 713 KB

english, 2015

24

N-Phenyl-N′-(2-chloroethyl)ureas (CEUs) as potential antineoplastic agents. Part 3: Role of carbonyl groups in the covalent binding to the colchicine-binding site

Emmanuel Moreau, Sébastien Fortin, Jacques Lacroix, Alexandre Patenaude, Jean L.C. Rousseau, René C-Gaudreault

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 290 KB

english, 2008

25

Styryl-N-phenyl-N′-(2-chloroethyl)ureas and styrylphenylimidazolidin-2-ones as new potent microtubule-disrupting agents using combretastatin A-4 as model

Gagné-Boulet, Mathieu, Fortin, Sébastien, Lacroix, Jacques, Lefebvre, Carole-Anne, Côté, Marie-France, C.-Gaudreault, René

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.33 MB

english, 2015

26

Selective alkylation of βII-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents

Jessica S. Fortin, Marie-France Côté, Jacques Lacroix, Michel Desjardins, Éric Petitclerc, René C.-Gaudreault

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 884 KB

english, 2008

27

ChemInform Abstract: Antimitotic Antitumor Agents: Synthesis, Structure—Activity Relationships, and Biological Characterization of N-Aryl-N′-(2-chloroethyl)ureas as New Selective Alkylating Agents.

Emmanuelle Mounetou, Jean Legault, Jacques Lacroix, Rene C-Gaudreault

Journal:

Year:

2001

File:

PDF, 29 KB

2001

28

Aromatic 2-chloroethyl urea derivatives and bioisosteres. Part 2: Cytocidal activity and effects on the nuclear translocation of thioredoxin-1, and the cell cycle progression

Jessica S. Fortin, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, René C.-Gaudreault

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 929 KB

english, 2008

29

Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site

Sébastien Fortin, Jacques Lacroix, Marie-France Côté, Emmanuel Moreau, Éric Petitclerc, René C.-Gaudreault

Journal:

Biological Procedures Online

Year:

2010

Language:

english

File:

PDF, 187 KB

english, 2010

30

Dr. Lacroix replies

Lacroix, Jacques, Gaudreault, Pierre, Gauthier, Marie

Journal:

Critical Care Medicine

Year:

1990

File:

PDF, 77 KB

1990

31

Population Pharmacokinetics of Terfenadine

Richard L. Lalonde, Denis Lessard, Jacques Gaudreault

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 1.03 MB

1996

32

Development of a Focused Pharmacogenomics Panel To Predict the Effects of Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Heart Failure

Simon de Denus, Nathalie Gaudreault, Jacques Turgeon, Michel White, Michael S. Phillips

Journal:

Journal of Cardiac Failure

Year:

2007

Language:

english

File:

PDF, 208 KB

english, 2007

33

M-F-060 CEREBRAL DYSFUNCTIONS IN RAPID EYE MOVEMENT SLEEP BEHAVIOUR DISORDER: AN EVENT-RELATED POTENTIAL STUDY

Pierre-Olivier Gaudreault, Jacques Y. Montplaisir, Jean-François Gagnon, Mélanie Vendette, Nadia Gosselin

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

34

Anticonvulsant pharmacodynamics and disposition of triazolam in rats

Jacques Gaudreault, France Varin, Gary M. Pollack

Journal:

Journal of Pharmaceutical Sciences

Year:

1996

Language:

english

File:

PDF, 142 KB

english, 1996

35

Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships

Sébastien Fortin, Lianhu Wei, Emmanuel Moreau, Jacques Lacroix, Marie-France Côté, Éric Petitclerc, Lakshmi P. Kotra, René C. Gaudreault

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.27 MB

english, 2011

36

ChemInform Abstract: Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl)benzenesulfonamides as Antimitotics. Antiproliferative, Antiangiogenic and Antitumoral Activity, and Quantitative Structure—Activity Relationships.

Sebastien Fortin, Lianhu Wei, Emmanuel Moreau, Jacques Lacroix, Marie-France Cote, Eric Petitclerc, Lakshmi P. Kotra, Rene C. Gaudreault

Journal:

Year:

2012

Language:

english

File:

PDF, 13 KB

english, 2012

37

Intramolecular cyclization of N-phenyl N′(2-chloroethyl)ureas leads to active N-phenyl-4,5-dihydrooxazol-2-amines alkylating β-tubulin Glu198 and prohibitin Asp40

Anna Trzeciakiewicz, Sébastien Fortin, Emmanuel Moreau, René C.-Gaudreault, Jacques Lacroix, Christophe Chambon, Yves Communal, Jean-Michel Chezal, Elisabeth Miot-Noirault, Bernadette Bouchon, Françoi

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 501 KB

english, 2011

38

Absence of Pharmacodynamic Interaction Between Inclacumab and Heparin in Healthy Smokers

Schmitt, Christophe, Mudie, Nadejda, Ciorciaro, Cornelia, Gaudreault, Jacques

Journal:

Journal of Cardiovascular Pharmacology

Year:

2015

Language:

english

File:

PDF, 336 KB

english, 2015

39

In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity at CYP-450

Philippe Labrie, Shawn. P. Maddaford, Jacques Lacroix, Concettina Catalano, David K.H. Lee, Suman Rakhit, René C. Gaudreault

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 324 KB

english, 2006

40

Ranibizumab inhibits multiple forms of biologically active vascular endothelial growth factor in vitro and in vivo

John Lowe, James Araujo, Jihong Yang, Mike Reich, Amy Oldendorp, Vanessa Shiu, Valerie Quarmby, Henry Lowman, Samantha Lien, Jacques Gaudreault, Mauricio Maia

Journal:

Experimental Eye Research

Year:

2007

Language:

english

File:

PDF, 185 KB

english, 2007

41

A New Generation of N-Aryl-N‘-(1-alkyl-2-chloroethyl)ureas as Microtubule Disrupters: Synthesis, Antiproliferative Activity, and β-Tubulin Alkylation Kinetics

Mounetou, Emmanuelle, Legault, Jean, Lacroix, Jacques, C.-Gaudreault, René

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 136 KB

english, 2003

42

In vitro activity of novel dual action MDR anthranilamide modulators with inhibitory activity on CYP-450 (Part 2)

Philippe Labrie, Shawn P. Maddaford, Jacques Lacroix, Concettina Catalano, David K.H. Lee, Suman Rakhit, René C. Gaudreault

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 300 KB

english, 2007

43

Design, Synthesis, Biological Evaluation, and Structure–Activity Relationships of Substituted Phenyl 4-(2-Oxoimidazolidin-1-yl)benzenesulfonates as New Tubulin Inhibitors Mimicking Combretastatin A-4

Fortin, Sébastien, Wei, Lianhu, Moreau, Emmanuel, Lacroix, Jacques, Côté, Marie-France, Petitclerc, Éric, Kotra, Lakshmi P., C.-Gaudreault, René

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 4.72 MB

english, 2011

44

Activation of Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonates Prodrugs by CYP1A1 as New Antimitotics Targeting Breast Cancer Cells

Fortin, Sébastien, Charest-Morin, Xavier, Turcotte, Vanessa, Lauvaux, Coraline, Lacroix, Jacques, Côté, Marie-France, Gobeil, Stéphane, C.-Gaudreault, Rene

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 28.35 MB

english, 2017

45

Synthesis and growth inhibition activity of fluorinated derivatives of tamoxifen

Malo-Forest, Bianca, Landelle, Grégory, Roy, Jessye-Ann, Lacroix, Jacques, Gaudreault, René C., Paquin, Jean-François

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 579 KB

english, 2013

46

Alkylation potency and protein specificity of aromatic urea derivatives and bioisosteres as potential irreversible antagonists of the colchicine-binding site

Jessica S. Fortin, Jacques Lacroix, Michel Desjardins, Alexandre Patenaude, Éric Petitclerc, René C.-Gaudreault

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 523 KB

english, 2007

47

Synthesis, Biological Evaluation, and Structure–Activity Relationships of Novel Substituted N -Phenyl Ureidobenzenesulfonate Derivatives Blocking Cell Cycle Progression in S-Phase and Inducing DNA Double-Strand Breaks

Turcotte, Vanessa, Fortin, Sébastien, Vevey, Florence, Coulombe, Yan, Lacroix, Jacques, Côté, Marie-France, Masson, Jean-Yves, C.-Gaudreault, René

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.83 MB

english, 2012

48

PHARMACEUTICAL SOCIETY.

Malo-Forest, Bianca, Landelle, Grégory, Roy, Jessye-Ann, Lacroix, Jacques, Gaudreault, René C., Paquin, Jean-François

Journal:

Year:

1841

Language:

english

File:

PDF, 245 KB

english, 1841

49

Complexation of VEGF with Bevacizumab Decreases VEGF Clearance in Rats

Vanessa Hsei, Geralyn G. DeGuzman, Allison Nixon, Jacques Gaudreault

Journal:

Pharmaceutical Research

Year:

2002

Language:

english

File:

PDF, 65 KB

english, 2002

50

Antimitotic Antitumor Agents: Synthesis, Structure−Activity Relationships, and Biological Characterization of N-Aryl-N‘-(2-chloroethyl)ureas as New Selective Alkylating Agents

Mounetou, Emmanuelle, Legault, Jean, Lacroix, Jacques, C-Gaudreault, René

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 249 KB

english, 2001

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